One factor is diseases that are spread by people. For example a sexuallt transmitted disease can prevent reproduction because organisms with these diseases may not be able to reproduce at a healthy rate and death may come from these matters. Another form of this is predation. Predators have to get their share of food and by doing this, they kill other animals and ruin habitats in the process. Obviously this can happen with humans as it happens to animals. The last reason can be natural destruction. Human nature is very random which means you never see it coming. You never know when a hurricane or an earthquake might hit and destroy many habitats. Which can cause many species to instinct.
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